Obesity Abstracts

The study determines the prevalence and lifestyle predictors of metabolic health (MH) among normal weight and obese individuals within a Maltese cohort using two main approaches a) the Metabolic Syndrome (Met-S) framework as per NCEP-ATPIII and b) Insulin Resistance (IR) as defined by HOMA-IR; and to determine which cut-off valueof HOMA-IR best predicts metabolic health. This was a cross sectional study. Subjects with a BMI <25 kg/m2 were considered normal weigh...

Background: Not all obese individuals exhibit abnormal cardiometabolic parameters. These are termed as being metabolically healthy obese (MHO). Conversely some normal weight individuals exhibit adverse cardiometabolic parameters and are described as being metabolically unhealthy normal weight (MUHNW). Visceral adiposity is known to be strongly associated with cardiometabolic risk than subcutaneous adiposity. Furthermore, there are gender differences in distribution of fat and ...

Background: Several studies have investigated the association between vitamin D receptor (VDR) variants and the risk of cardiometabolic complications. The pleiotropic action of VDR in extra-skeletal tissues gives physiologic plausibility to the associations between VDR variants and metabolic health, particularly in obese individuals. Whilst multiple conflicting findings have been reported, clinical data has shown that despite an increase in physical activity and nurturing heal...